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Evaluation of Magnetic and Thermal Properties of Ferrite Nanoparticles for Biomedical Applications
Asahi Tomitaka,Minhong Jeun,Seongtae Bae,Yasushi Takemura 한국자기학회 2011 Journal of Magnetics Vol.16 No.2
Magnetic nanoparticles can potentially be used in drug delivery systems and for hyperthermia therapy. The applicability of Fe₃O₄, CoFe₂O₄, MgFe₂O₄, and NiFe₂O₄ nanoparticles for the same was studied by evaluating their magnetization, thermal efficiency, and biocompatibility. Fe₃O₄ and CoFe₂O₄ nanoparticles exhibited large magnetization. Fe₃O₄ and NiFe₂O₄ nanoparticles exhibited large induction heating. MgFe₂O₄ nanoparticles exhibited low magnetization compared to the other nanoparticles. NiFe₂O₄ nanoparticles were found to be cytotoxic, whereas the other nanoparticles were not cytotoxic. This study indicates that Fe₃O₄ nanoparticles could be the most suitable ones for hyperthermia therapy.