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        한국산 창출의 성분연구

        임동술(Dong Sool Yim),유승조(Seung Cho Yu),지형준(Hyung-Joon Chi) 한국생약학회 1988 생약학회지 Vol.19 No.4

        From the rhizome of Atractylodes japonica Koidzumi (Compositae) which is the original plant of oriental medicine Cang-Zhu, four essential oil compounds were isolated. Three of them were identified as atractylon, hydroxyatrac tylon and 5αH, 10β-selina-4(14), 7(11)-dine-8-one, which were already known as the constitutents of Atractylodes Rhixoma. The fourth is a novel polyacetylene type compound, and the structure is postulated as 1, 4-diacetoxytetradeca-6, 12-diene-8, 10-diyne by the spectral data.

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        호장의 생약학적 연구 (III) : 둥근잎호장근경의 성분연구

        지형준(Hyung-Joon Chi),최정림(Jung-Rim Choi),유승조(Seung-Cho Yu) 한국생약학회 1982 생약학회지 Vol.13 No.4

        Three species of genus Polytonum, namely P. cuspidatum, P. sachalinense and P. ellipticum are distributed in Korea. Polygonum ellipticum Migo is a perennial herb in Polygonaceous plants. The root of the plant (Polygoni Rhizoma, Ho-Jang) have been used as laxative, diuretic and for the treatment suppurative dermatitis in the oriental medicine. As the part of the study for the comparison of the three species in their components, the authors attempted to isolate the anthraquinones and stilbene derivative from the rhizome of P. ellipticum. The methanolic extract of dried rhizome of this plant was fractionated into ether soluble and insoluble fraction and each fraction was applied to column chromatography to isolate above mentioned components. Anthraquinone derivatives were isolated first: comp. I, mp 204∼205°(physcion), comp. II, mp 254∼255°(emodin), comp. IV, mp 191∼192°(emodin-8-O-β-D-glucoside) and comp. III, mp 280∼282°(β-sitosterol-glucoside). They were identified by chemical properties and UV, IR and NMR spectra and by the direct comparison with authentic samples. Stilbene derivative was isolated secondly; comp. V, mp 255∼256°which was reported to possess antibacterial and antifungal activities.

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