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피부장벽 개선에 효과적인 추출물 및 화합물에 관한 연구동향
왕혜민(Hye-Min Wang),박초희(Cho-Hi Park) 한국화장품미용학회 2020 한국화장품미용학회지 Vol.10 No.1
Skin barrier refers to the stratum corneum of epidermis, which is explained by the Brick and mortar theory. The purpose of this study is to examine the literature on the effects of skin barrier and to present the research trends on skin barrier improvement in the future through the results of the study on how the extracts and compounds relate to atopic dermatitis. Based on Googles academic search and academic research information service, the study examined extracts and compounds that were effective in improving skin barriers. Among the extracts that are effective in improving skin barriers, the number of papers demonstrated through experiments was the highest in 2010, and the number of experimental studies that showed efficacy in improving skin barriers in compounds was the highest in 2003. Extracts have been studied the most so far with four cases of oats and Houttuynia cordata Thunb and compounds with five cases of seramide have been studied the most. Research on atopic dermatitis has continued steadily, but the clear cause has not been identified to this day, so methods to prevent and improve atopic dermatitis and inflammatory diseases will have to be continuously researched and developed in the future with extracts and compounds of various natural materials.
뇌성마비 환아 중증도별 시각화척도, 시간교환법, EQ-5D-Y Proxy를 이용한 삶의 질 측정
이고은 ( Go-eun Lee ),김남권 ( Nam Kwen Kim ),윤영주 ( Young Ju Yun ),왕혜민 ( Hye Min Wang ),김정훈 ( Jeong Hun Kim ),이동효 ( Dong Hyo Lee ) 대한한방신경정신과학회 2017 동의신경정신과학회지 Vol.28 No.2
Objectives: To measure the quality of life in patients according to virtual cerebral palsy severity by using the Korean version of EQ-5D-Y proxy, Visual Analogue Scale (VAS), and Time Trade-Off method (TTO). Methods: The study was conducted in parents of children and adolescents aged 4 to 15 years in Seoul. We analyzed the difference in the utility value according to five levels of cerebral palsy severity in the Gross Motor Function Classification System (GMFCS) and test-retest reliability. Results: 1. There were significant differences in VAS, TTO, and EQ-5D-Y proxy according to the cerebral palsy severity (p<.001). 2. VAS was significantly different according to the respondent`s visit to the medical institution, the presence of disease in the respondent, a visit to the child`s medical institution, the age of the child, and the sex of the child. The value of TTO was significantly different according to the respondent`s visit to the medical institution, respondent`s sex, and the age of the child. Also, EQ-5D-Y proxy was significantly different according to the age of the child. 3. Intraclass correlation coefficient values were more than 0.6 for both VAS and TTO at all stages. But for the EQ-5D-Y proxy, the value was less than 0.6 at all stages. Conclusions: The quality of life assessment using EQ-5D-Y proxy showed significant differences in the severity of cerebral palsy. However, large-scale studies using EQ-5D-Y proxy are needed because of low test-retest reliability.