익기보혈탕(益氣補血湯)물 추출물이 PTU로 유발된 Rat의 갑상선기능저하증에 미치는 영향

손지혜 ( Ji Hye Son ),김동철 ( Dong Chul Kim ) 대한한방부인과학회 2015 大韓韓方婦人科學會誌 Vol.28 No.3

Objectives: The object of this study was to evaluate the effect of Yikgeebohyul-tang aqueous extracts (YKBHT) on the propylthiouracil (PTU)-induced rat hypothyroidism. Methods: The rats were divided into 6 groups : intact vehicle control, PTU control, LT4, YKBHT 500, 250 and 125 mg/kg treated groups. Hypothyroidism was induced by daily subcutaneous treatment of PTU 10 mg/kg for 28 days. YKBHT aqueous extracts were administered once a day as an oral dose of 500, 250 and 125 mg/kg for 42 days. The changes were observed : weight of body, thyroid gland, liver, testis, epididymis and prostate, serum thyroid hormone levels, serum male sex hormone levels, serum lipid profiles, liver and testis antioxidant system. These results were compared with LT4 0.5 mg/kg intraperitoneally treated rats. Results: These PTU induced hypothyroidism and related hepatic and male reproductive organ damages were favorably and dose-dependently inhibited by treatment of YKBHT 500, 250 and 125 mg/kg, and YKBHT also effectively regulated the PTU-induced abnormal antioxidant defense factor changes in the both liver and testis. Although, LT4 also inhibited PTU-induced hypothyroidism and relative liver damages. But it deteriorated the hypothyroidism related testis, epididymis and prostate damages through testicular oxidative damages. Conclusions: The result of this study suggests that YKBHT has favorable effects on the hypothyroidism and related liver and reproductive organ damages with augmentation of antioxidant defense factor in the testis and liver. YKBHT 500, 250 and 125 mg/kg dose-dependently inhibited PTU-induced hypothyroidism and related liver and male reproductive organ damages in rats.

국내 종합병원의 공용공간에서 나타나는 군집유형과 이용행태에 관한 조사 연구

손지혜(Son, Ji-Hye),양내원(Yang, Nae-Won) 한국실내디자인학회 2009 한국실내디자인학회논문집 Vol.18 No.5

Recently general hospitals in Korea are focusing on healing environment which care for patients on the side of spirit and psychology without medical treatment. For the reason, architects are planning a public space on a large scale in which can be held cultural performances and artistic events. Those of social activities can be effective healing environment according to the "Anthroposophical medicine" studied by Rudolf Steiner. To the patient, Social healing environment is relation with normal life and back to the life. The case of a large-scale public space on hospital in foreign country shows the effect of healing environment through social community. So it is valuated as a social healing environment and community space. Even though the large-scale public space has been being increased in our circumstance, there is no evaluation of use on it. So there is no idea how people are satisfied with public space to stay and form a concourse by themselves. The purpose of this study is to find out the desire of people, who use the large-scale public space by analysis of observation research and interview in the general hospitals. And finally this study suggests the factors which can realize social healing environment on the planning of public space in hospital architecture.

동,서양의 치유환경 관점의 차이에 관한 연구

손지혜 ( Ji Hye Son ),양내원 ( Nae Won Yang ) 한국의료복지건축학회 2015 의료·복지 건축 Vol.21 No.4

Purpose: The definition of healing and treatment is different between the East and the West. I suppose that the different definitions of them affect the notion of healing environment in two cultural area. Therefore the aim of this study is to consider the different perspective in healing environment between the East and the West. Methods: Relevant literature review around domestic and foreign reference in fields of medicine and architecture has been conducted to consider the purpose. Results: First, the perspective that the cause of disease stems from inside of body approaches the body from standpoint of healing for recovery. Healing is the way to conquer imbalance by entering into a connection with nature around body. The concept of healing could analyze that it come from relevant perspective. Second, the healing environment in the East is the place where the flow of Qi between, human and human, and, human and environment, keep a balance. The notion of healing environment in the East is the filed of relations. In the West, the notion of healing environment is the place where arouse fine emotions through sensory stimulations. Implications: Recently the studies of healing environment focus on deducing sensory stimulation factors scientifically in the perspective of the West. But the healing environment couldn``t be possible without the notion of place of relations. In the future, the notion of healing environment as the field of relations in the East has to be concerned.

종설(綜說) : 일개 지역 보건소 한방 비만교실을 통한 비만 치료 결과에 대한 고찰

손지혜 ( Ji Hye Son ) 대구한의대학교 제한동의학술원 2012 東西醫學 Vol.37 No.1

Objective: The purpose of this study is to prove an oriental medicine cure for obesity. Recently many people interest in obesity because it makes a lot of problems such as hypertension, arteriosclerosis, DM and so on. Methods: From September 2006 to December 2006, we practiced general treatment of the auricular acupuncture, electro-acupuncture, moxibustion, cupping, ow frequency therapy and herbal medicine for 30 outpatients in Sangju public health center. Results: The changes in body weight, degree of obesity, BMI, waist measurement, hip circumference, WHR and TG were significant. But The changes in body fat ratio, abdominal fat ratio, glucose, LFT, Cholestrol, and CBC were not significant.

국내 의료시설 기본설계 과정에서 나타나는 치유환경개념의 반영 특성에 관한 연구

손지혜(Son, Ji-Hye),양내원(Yang, Nae-Won) 대한건축학회 2012 대한건축학회논문집 Vol.28 No.7

Healing environment is one of the most important concept of healthcare architecture planning through increasing an interest in qualitative development of healthcare architecture. Existing studies of post occupancy evaluation(POE) has been analyzed by healing environmental criteria which doesn"t affect decision of architect in schematic design but is confined to evaluating architecture by researchers. Therefore it is difficult that verify the healing effect of space designed by healing environmental criteria proving from studies of architectural planning. The purpose of this study is how healing environmental concept and criteria are concerned in department planning and characteristics of space in schematic design. For this study, the prizewinner of healthcare architecture design competition since 2000 are analyzed by standards of healing environmental concept and criteria which was arranged by staffs of architecture. From this study, first, healing environmental design is more considered in ward, public space and exterior in hospital planning.. Second, nature environment is the most important design factor. Third, patients" privacy and daily life of their family are not well considered in the planning of hospital. Fourth, social support for patient is considered in not general wards but special wards.

자폐스펙트럼장애 아동의 사회적 상호작용 증진을 위한 동물매개중재의 치료적 효과에 대한 고찰

손지혜(Son, Ji-Hye),강소연(Kang, So-Yeon),강슬기(Kang, Seul-Gi),손유진(Son, Yu-Jin),정예진(Jong, Ye-Jin),최재향(Choi, Jae-Hyang) 한국정신보건작업치료학회 2021 한국정신보건작업치료학회지 Vol.8 No.1

목적 : 본 연구는 동물매개중재가 자폐스펙트럼장애 아동의 사회적 상호작용에 미치는 영향, 치료적 효과를 알아보고, 자료분석을 통해 얻은 정보를 동물매개중재에 관심을 가지고 있는 임상가와 작업치료사에게 기초 자료로 제공하고자 하였다. 연구방법 : 전자 데이터베이스인 RISS, Google Scholar, Korea Scholar를 사용하여 2007년 부터 2020년까지의 논문을 검색하였다. 주요 검색어는 ( 자폐스펙트럼장애 OR ASD OR Autism Spectrum Disorders ) AND ( 사회적 상호작용 OR 사회성 AND 동물매개중재 OR 반려견 OR Animal therapy OR Animal-assisted )를 사용하였다. 최종적으로 10편의 국내외 논문을 본 연구의 분석 대상으로 선정하였다. 선정된 논문은 저자/연도, 연구 목적, 대상자 N/ 나이, 기간/빈도, 중재 프로그램, 프로그램 제공자, 측정도구, 결과 순으로 정리하였다. 결과 : 중재 도우미 동물은 반려견, 기니피그, 말 3종류로 나타났다. 제공자는 동물매개심리상담사 8명을 포함하여 총 27명이며 지역사회 환경을 기반으로 프로그램이 진행됐다. 사용된 도구로는 사회성숙도검사(SMS)가 가장 많았다. 동물매개중재의 치료적 효과는 사회적 기술 향상에 가장 효과적이었고 다음으로 부정적 사회행동의 감소로 나타났다. 결론 : 본 연구는 동물매개중재 프로그램에 대한 체계적 고찰을 통하여 관련 영역을 확대하는 기초 자료를 마련하고자 하였다. 이는 추후 작업치료사가 동물매개중재(AAI) 전문가로서의 역할을 정립할 수 있는 후속연구를 계획하는 기초 자료로 활용되기를 기대한다. Objective : The aim of this systematic review is to investigate the effects of animal assisted interventions on social interaction and therapeutic effects to ASD, and provide the information obtained through data analysis as basic data to occupational therapists. Methods : Previous studies were found from an electronic database; RISS, Google Scholar, Korea Scholar database published between 2007 to 2020. The key terms were ASD OR Autism Spectrum Disorders AND Social interaction AND AAI OR Dog OR Animal therapy OR Animal-assisted . A total of 10 articles were used in this analysis. Results : Types of intervention included dogs, guinea pigs and horses. The provider was a total of 27 people, including 8 AAI experts, and the program was based on the community environment. The Social Maturity Scale(SMS) was the most used measurement tool. As the result of the intervention social skills were improved and negative social behaviors were decreased. Conclusion : This study was to provide basic data for expanding related areas through a systematic review of animal assisted interventions. In the future, the roles of occupational therapists should be clarified of animal assisted intervention and various animal assisted interventions should be made.

달크로즈 유리드믹스 음악프로그램이 만5세 유아의 행복감과 스트레스에 미치는 영향

손지혜 ( Son Ji-hye ) 한국달크로즈유리드믹스학회 2016 국내학술심포지엄 Vol.2016 No.-

본 연구는 달크로즈 유리드믹스 음악프로그램이 유아의 행복감, 유아 스트레스에 미치는 효과를 알아보기 위한 목적으로 이루어졌다. 연구대상은 S시의 소재한 S선교원에 다니는 만5세 유아 24명(남아 12명, 여아 12명)이 참여하였고, 11주에 걸쳐 주 1회씩 11회기 달크로즈 유리드믹스 음악프로그램을 진행하여 연구 분석하였다. 스토리텔링을 기반으로 유아들의 친숙한 소재를 선정하여 MYK 문연경 유리드믹스 음악 프로그램을 통해 다양한 악기연주, 클래식통합예술활동으로 프로그램을 구성하였다. 자료처리는 SPSS 18.0 프로그램을 사용하였고 연구문제에 따라 유아의 행복감, 유아의 스트레스, 유아의 행복감 하위요소의 상관관계를 알아보기 위해 대응표본 t검증, 독립표본 t검증, Pearson의 적률 상관분석을 실시하였다. 연구결과, 유아의 행복감과 유아의 스트레스에 긍정적인 영향을 미치는 것으로 나타났으며 유아 행복의 하위요소인 친구관계와 정서영역, 몰입영역에 유의한 정적상관관계가 나타났다. 이를 통해 달크로즈 유리드믹스 음악프로그램이 유아의 행복감 증진에 효과적인 교수 방법임을 시사하며, 유아교육현장에서 달크로즈 유리드믹스 음악프로그램을 적극적으로 실시하기 위한 지원 방안모색이 필요함을 제언한다. This study aims to examine the effect of the Dalcroze Eurhythmics music program on the five-year-old children`s happiness, young children`s stress. As the subjects of this study, 24 five-year-old children(12 boys, 12 girls) in S children`s missionary center in S city were participated, and the research and analysis were carried out by 11 sessions of the Dalcroze Eurhythmics music program for once a week during 11 weeks. Based on the storytelling, the familiar material for young children was selected, so the MYK Moon Yeon Kyoung`s Eurhythmics music program was used for the program which was composed with playing various musical instruments, and the classic integrated arts activities. For the data-processing, the SPSS 18.0 program was used by the research problems, and the corresponding sample t-test, independent samples t-test, and the Pearson`s product-moment correlation analysis were conducted to examine the correlation between the sub-elements such as the five-year-old children`s happiness, young children`s stress, five-year-old children`s happiness. In the result of study, it had positive impact on the five-year-old children`s happiness and the young children`s stress, and the sub-elements of the children`s happiness such as the peer relationship, the emotional area, and the immersion area showed the significant positive correlation. Therefore, it implies that the Dalcroze Eurhythmics music program is the effective teaching methods for the five-year-old children`s happiness promotion, and it suggests that the support measures for conducting the Dalcroze Eurhythmics music program in the education field for the young children actively should be found.

1인가구를 위한 식생활 특화 서비스 디자언 방향에 관한 연구

손지혜(Ji Hye Son),최명식(Myoung Sik Choi) 경희대학교 산학협력단 예술디자인연구원 2014 예술· 디자인학연구 Vol.17 No.1

병동부 공용공간 평면 유형 및 환경 특성과 이용자 체류의 상관관계

손지혜(Son, Ji-Hye),양내원(Yang, Nae-Won) 대한건축학회 2017 대한건축학회논문집 Vol.33 No.6

This study focus on the type and features of the place where the frequency of users’ stay could be increased for social healing in wards. For analysis of the users stay position and behaviors, a field study method is used. Conclusion of this study is following. First when dayroom, program room and balcony are planned, the size of them should be avoided being planned as the least area. And it is desirable that these places are planned with the type of combination with corridor and are separate from a nursing station. Second the type of Corridor which are One-way corridor and corridor with courtyard is desirable. And seating places should be planned nearby one-way corridor and courtyard. Third when the corridor is planned, the alcove where personal behaviors and private territorialization are possible should be placed nearby natural lighting spaces.

체외수정 후 태동부안(胎動不安)이 발생한 환자 치험 1례

손지혜 ( Ji Hye Son ),김동철 ( Dong Chul Kim ) 대한한방부인과학회 2014 大韓韓方婦人科學會誌 Vol.27 No.3

Objectives: We designed this study to evaluate the effect of Korean medicaltreatment on complications of chemotherapy after curative resection in patientwith ovarian carcinomaⅣ. Methods: The patient got total abdominal hysterectomy and bilateral salpingooophorectomy(TAHBSO) on 9/4 and received chemotherapy on 10/7, 10/28, 11/18. During this period, the patient suffered from anorexia, dyspepsia, nausea, weightloss and insomnia. We treated the patient with herbal medicine and acupuncture. The efficacy of treatment was evaluated with visual analog scale (Vas), weightand 36-item short form health survey instrument (SF-36). Results: After treatment, although the scale values went ups and downs accordingto chemotherapy schedule, abdominal pain Vas changed 7 to 0, weight changed46 kg to 51 kg. Also, SF-36 scores increased. Conclusions: This case report shows that the Korean medical treatment isuseful in the treatment of complications of chemotherapy after curative resectionin patient with ovarian carcinomaⅣ.