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정성제 ( Jeong Seong Je ),이진희 ( Lee Jin Hui ),송효남 ( Song Hyo Nam ),성낙술 ( Seong Nag Sul ),이승은 ( Lee Seung Eun ),백남인 ( Baeg Nam In ) 한국응용생명화학회 2004 Applied Biological Chemistry (Appl Biol Chem) Vol.47 No.1
The antioxidant activities of 80% methanol extracts obtained from 118 medicinal plants were tested through the evaluation of DPPH and superoxide anion radicals scavenging activity. Methanol extracts of Sophora japonica (76.9%) and Camptotheca acuminata Dence (50.9%) were found to have more than 50% DPPH radical scavenging activity while those of Perilla frutescens (37.2%), Amomum costatum (34.9%), Prunus ansu (33.2%), Mentha arvensis (32.3%), Serratula koreana (32.2%), Eriobotrya japonica (30.5%), and Artemisia asiatica (30.5%) showed more than 30% scavenging activity. Even though all of the commercial antioxidants didn`t show superoxide anion radical activity, Mentha arvensis (87.7%), Eriobotrya japonica (84.9%), Amomum costatum (82.9%), Camptotheca acuminata Dence (82.1%) showed more than 80% scavenging activity. Mentha arvensis, Eriobotrya japonica, Amomum costatum, Camptotheca acuminata Dence showed strong antioxidative activity in the both DPPH and superoxide anion radical scavenging activities.
굴피나무(Platycarya strobilacea) 지상부로부터 항진균성 활성물질 분리
최용화 ( Choe Yong Hwa ),채상기 ( Chae Sang Gi ),김진호 ( Kim Jin Ho ),강상재 ( Gang Sang Jae ),백남인 ( Baeg Nam In ),한재택 ( Han Jae Taeg ) 한국응용생명화학회 2003 Applied Biological Chemistry (Appl Biol Chem) Vol.46 No.3
Methanol extract obtained from aerial parts of Platycarya strobilacea was successively fractionated with ??-hexane, ethylacetate, ??-botanol, and water. From ethylacetate fraction, an active compound was isolated through repeated silica gel column chromatography and was identified as 5-hydroxy-2-methoxy-1,4-naphthoquinone by MS and NMR analyses. The compound showed in vivo 76% antifungal activity at 100 ㎍/m/ against tomato late blight disease.
식용 식물자원으로부터 활성물질의 탐색-8. 용안육(Euphoria longana L.)으로부터 분리된 uridine의 혈소판 응집 저해 효과
김동현 ( Kim Dong Hyeon ),송명종 ( Song Myeong Jong ),최정민 ( Choe Jeong Min ),김성훈 ( Kim Seong Hun ),김대근 ( Kim Dae Geun ),정인식 ( Jeong In Sig ),박미현 ( Park Mi Hyeon ),권병목 ( Kwon Byeong Mog ),백남인 ( Baeg Nam In ) 한국응용생명화학회 2004 Applied Biological Chemistry (Appl Biol Chem) Vol.47 No.1
The arils of Euphoria longana L. was extracted with 80% aqueous MeOH, and the concentrated extract was partitioned with EtOAc, H-BuOH and H₂O. From the n-BuOH fraction, four compounds were isolated through the repeated silica gel, ODS and Sephadex LH-20 column chromatographies. From the result? of physico-chemical data including NMR, MS and IR, the chemical structures of the compounds were determined as 1,1-dimethyl-2-propenyl 1-O-β-D-glucopyranoside. ethyl β-D-glucopyranoside, 5-(hydroxymethyl)-2-furfur-aldehyde and uridine. Uridine exhibited inhibition effect of 79% on platelet aggregation at the concentration of ㎍/㎖.