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김상균 ( Sang Kyoon Kim ),유창우 ( Chang Woo You ),권혁진 ( Hyeok Jin Kwon ),정혜진 ( Hey Jin Jeong ),김성훈 ( Seong Hun Kim ),김인희 ( In Hee Kim ),이승옥 ( Seung Ok Lee ),이민로 ( Min Ro Lee ),장규윤 ( Kyu Yun Jang ),김상욱 ( Sa 대한소화기기능성질환·운동학회 2006 Journal of Neurogastroenterology and Motility (JNM Vol.12 No.2
Colonic hypoganglionosis is one variant of the colonic ganglion cell disorders. It is characterized histologically by a small number of ganglion cells in the intestinal myenteric plexuses and it`s characterized functionally by severely impaired gut motility. Most cases reported in the literature have occurred relatively late in childhood, and they usually involve mild constipation. In our case, the patient had a megacolon with severe constipation. He had had repeated admissions due to chronic constipation and abdominal distention. Conservative management failed to relieve those symptoms, and so subtotal colectomy was undergone. The patient recovered normal bowel habits in five months after his operation. (Kor J Neuro-gastroenterol Motil 2006;12:161-165)