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      • KCI등재

        일부공단지역에 거주하는 성인남성의 알레르기 반응과 산화손상에 대한 연구

        기영선,민진영,유홍식,백도명,Ki, Young-Sun,Min, Jin-Young,Yoo, Hong-Sik,Paek, Do-Myung 한국환경보건학회 2008 한국환경보건학회지 Vol.34 No.2

        Allergic diseases have been dramarically increased over recent years, especially in industrialized countries. Oxidative stress has been believed to playa significant role in the occurrence of the allergic inflammatory responses. Although previous studies concerning oxidative stress and systemic inflammation have been reported, few data is available, and other allergic diseases, except for asthma, are hardly studied about the association with oxidative stress. This study evaluated the relationship between allergic disease and Malondialdehyde (MDA) as an indicator of oxidative stress. The study population was 197 male adults living in an industrial area. The ISAAC questionnaire was used to confirm wheezing and rhinitis, and atopy was evaluated by skin prick test. MDA was analyzed by spectrophotometer. To examine bronchial hyperresponsiveness (BHR), methacholine test was performed, and the index of bronchial responsiveness (BR index) was calculated. We used multivariate logistic regression model and general linear model with SAS program. We found significant associations of MDA with brindex (p=0.023), rhinitis (p=0.016), atopy (p=0.03), adjusted by age, smoking, and body mass index (BMI). On the contrary, there was no significant difference of MDA with the status of asthma. Our result suggests that oxidative stress may playa major role in the occurrence of allergic response in male adults.

      • KCI등재

        기술노트 : 춘천시 일부 농촌 지역의 음용수 수질에 관한 조사연구

        박수정 ( Su Jung Park ),김문경 ( Moon Kyung Kim ),기영선 ( Young Sun Ki ),오소린 ( So Rin Oh ),신미연 ( Mi Yeon Shin ),오지윤 ( Ji Yoon Oh ),변재철 ( Jae Cheol Byeon ),이성민 ( Seong Min Lee ),정은희 ( Eun Hee Jung ),김은미 ( Eun 한국물환경학회 ( 구 한국수질보전학회 ) 2006 한국물환경학회지 Vol.22 No.3

        This study was conducted in the summer of 2005 in Shindong-myeon, Chuncheon-si, Gangwon-do to assess the quality of drinking water and to evaluate their potential pollutants. Ninety four water samples were collected from three classes of water supplies such as simple piped water, supplied own water and others (Supplied local water). Most residents used simple piped water (72.63%). 31.25% residents thought the water quality was bad and landfill was the main source of pollution that affected water quality. To correspond this perception, water quality was measured according to Drinking Water Quality Standard. The general bacteria, coliforms, and NO3-N exceeded the standard but the water qualities in these four areas were suitable for Drinking Water Quality Standard. The simple piped water showed low mean concentration of excess rate compared to supplied own piped water except general bacteria. Hardness, pH, and NO3-N showed significantly higher effects on drinking water quality. To evaluate the effect of effluent from landfill, water quality was measured according to distance and altitude. However, there was no effect of landfill effluent. To find out the effect of rainfall, we compared water quality of the year 2003 with that of 2005. The result showed significant differences in hardness and NO3-N concentration. This study confirmed that NO3-N, coliforms, and general bacteria are main pollutant of water supply in rural community. Therefore, it is necessary to regularly maintain simple piped water supply, supplement sewer facilities, and educate residents about public health risk associated with drinking water in rural area.

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