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RISS 인기검색어
- 검색키워드
- 저자 : ( Nevena Savic ) (검색결과 2 건)
- 무료
- 기관 내 무료
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( Miroslav Ilic ),( Ivan Kopitovic ),( Jovan Javorac ),( Darinka Kukavica ),( Nevena Savic ),( Danijela Vukosav ),( Nensi Lalic ) 대한결핵 및 호흡기학회 2021 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.129 No.-
Background The second category of tuberculosis (TB) patients present a tremendous problem for each subsequent treatment of tuberculosis and for society. The possibility of the appearance of resistant forms among these patients is more certain nowadays. The aim of this study was to analyze the possible problems that influence the Results of therapy among patients who belong to the second category. Methods This research included a 16-year period (from 2005 to 2020) at the Institute for Pulmonary Diseases of Vojvodina (Serbia). The effects of treatment were evaluated using univariate and multivariate logistic regression analysis. Results There were 223 treated patients in the second category; 17.1% of them were without elementary school education. Almost 50% were unemployed, while every fifth patient was an alcoholic or socially disadvantaged (compared to newly registered p=0.029). In the group of 45-64 years of age, there were 2/3 (149) of patients. Every third patient was treated for TB in youth, while 12% were treated for TB in the previous year. Most patients in this category had previous TB treatment - once (195, 87.4%) or twice (23, 10.3%). Extended regimens were implemented in almost 23% of patients (compared to newly registered p=0.018), while interrupted treatment as an outcome was observed in 21.3% of patients (p=0.008). Independent predictors for belonging to the second category were patients with/without elementary school (RR 1.278; 95% CI (1.108 - 2.573); p=0.032) and patients with alcoholic abuse (RR 2.806; 95% CI (1.683-4.758); p=0.029). Multivariate analysis identified the level of education as an independent predictor for being in the second category. Conclusions Vulnerable populations who were previously treated for TB need continuous monitoring with the aim of preventing resistant forms of the disease.
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Tracheobronchopathia Osteochlastica: A Study of 22 Patients from Serbia
( Jovan Javorac ),( Dejan Zivanovic ),( Miroslav Ilic ),( Ivan Kopitovic ),( Ana Milenkovic ),( Nevena Savic ) 대한결핵 및 호흡기학회 2021 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.129 No.-
Background Tracheobronchopathia osteochalstica (TO) is an indolent and rare airway disorder with a favourable prognosis, characterized by the presence of submucosal cartilage or bone nodules in the wall of the laryngotracheobronchial tree, that can lead to its narrowing. The aim of this study was to determine the frequency of this disorder in the general population, as well as to obtain basic socio-demographic characteristics of patients and the clinical manifestations of TO. Methods Endoscopic findings of patients who underwent bronchoscopy at the Institute for Pulmonary Diseases of Vojvodina, Serbia from 01.01.2013 to 01.01.2021 were analyzed. For patients in whom the existence of TO was confirmed, individual sociodemographic data were collected and clinical parameters were analyzed. Results Analysis of 14.545 bronchoscopic findings showed that TO was presented in 22 patients (0.15%). Our sample consisted of predominantly males (68.2%), while the mean age was 70.12. Approximately one-third of patients (32%) had a previously established respiratory disease (COPD and asthma most usually). In most cases, TO was found as an accidental finding during bronchoscopy indicated for other reasons (lung carcinoma in 50% of cases, inflammatory diseases of lung in 32%, other reasons in 18%). The trachea (especially its lower two-thirds) was the most common site of TO (73% of patients). The most common pre-bronchoscopic symptoms were cough, shortness of breath and chest pain. No significant narrowing of the laryngotracheobronchial lumen was found in any of the patients. Thus, none of them was treated with specific therapy for TO but received only symptomatic therapy and therapy aimed at the underlying respiratory disease. Conclusion Tracheobronchopathia osteochlastica is a rare and usually an underdiagnosed disorder. Its recognition can be important in everyday clinical practice, due to significant respiratory symptoms and impaired quality of life in patients with TO, as well as potential difficulties during endotracheal intubation.
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