한국의 산업집적과 지역화 : 1955-2002

이윤,구자형 한국생산성학회 2004 生産性論集 Vol.18 No.2

This paper presents the long-run trends in regional agglomeration and localization in Korean manufacturing. Regional agglomeration in Korea rose until the mid-1970's and has fallen substantially since then, while mass migration of rural residents to Seoul and its vicinity has continued. Localization also rose until the early 1980's and has fallen continuously. The trends of localization in Korea is comparable with that in the U.S manufacturing reported by Kim(1995). Analysis of regional agglomeration and localization shows that there does not exit any remarkable market failure or positive external economy which may justify government intervention in location of industries.

Financial Liberalization, Market Discipline And Bank Risk

( Ja Hyeong Koo ),( William C. Gruben ),( Robert R. Moore ) 한국금융연구원 2005 기타보고서 Vol.2005 No.1

Over-expression of a seed specific hevein-like antimicrobial peptide from Pharbitis nil enhances resistance to a fungal pathogen in transgenic tobacco plants

Koo, Ja-Choon,Chun, Hyun-Jin,Park, Hyeong-Cheol,Kim, Min-Chul,Koo, Yoon-Duck,Koo, Seong-Cheol,Ok, Hyun-Mi,Park, Soo-Jeong,Lee, Sung-Ho,Yun, Dae-Jin,Lim, Chae-Oh,Bahk, Jeong-Dong,Lee, Sang-Yeol,Cho, Mo Plant molecular biology and biotechnology research 2002 Plant molecular biology and biotechnology research Vol.2002 No.-

Two hevein-like peptides from the seed of Pharbitis nil, designated Pharbitis nil antimicrobial peptide 1 (Pn-AMP1) and Pn-AMP2, had been purified previously. Both exhibit potent in vitro antifungal activity against a broad spectrum of phytopathogenic fungi. We now report the isolation of two cDNA clones, designated pnAMP-h1 and pnAMP-h2, and the corresponding genomic clones encoding these protein suggests that the peptides are produced as a prepropeptide consisting of and N-terminal signal peptide, the mature protein and C-terminal domains. The transcripts of the two genes are accumulated seed-specifically, and the maximum transcripts are observed in the mid-to-late stage of seed development. Constitutive over-expression of the pnAMP-h2 cDNA in transgenic tobacco under the control of the cauliflower mosaic virus 35S promoter conferred enhanced resistance against the oomycete Phytophthora parasitica, the causal agent of black shank disease. Thus the Pn-AMPs may play a role in the protection of seeds and may

Characterization of a stamen-specific cDNA encoding a novel plant defensin in Chinese cabbage

Park, Hyeong-Cheol,Kang, Yun-Hwan,Chun, Hyun-Jin,Koo, Ja-Choon,Cheong, Yong-Hwa,Kim, Cha-Young,Kim, Min-Chul,Chung, Woo-Sik,Kim, Jong-Cheol,Yoo, Jae-Hyuk,Koo, Yoon-Duck,Koo, Sung-Chul,Lim, Chae-Oh,Lee Plant molecular biology and biotechnology research 2002 Plant molecular biology and biotechnology research Vol.2002 No.-

We isolated a stamen-specific cDNA, BSD1(Brassica stamen specific plant defensin 1)that encodes a novel plant defensin peptide in Chinese Chinese cabbage (Brassica campestris L. ssp. pekinensis). Plant defensins are antimicrobial peptides containing eight highly conserved cysteine residues linked by disulfide bridges. In BSD1, the eight cysteine residues and a glutamate residue at position 29 are conserved whereas other amino acid residues of the plant defensins consensus sequence are substituted. BSD1 transcripts accumulate specifically in the stamen of developing flowers and its level drops as the flowers mature. The recombinant BSD1 produced in Escherichia coli showed antifungal activity against several phytopathogenic fungi. Furthermore, constitutive over-expression of the BSD1 gene under the control of the cauliflower mosaic virus (CaMV) 35S promoter conferred enhanced tolerance against the Phytophthora parasitica in the transgenic tobacco plants.

Wearable Electrocardiogram Monitor Using Carbon Nanotube Electronics and Color-Tunable Organic Light-Emitting Diodes

Koo, Ja Hoon,Jeong, Seongjin,Shim, Hyung Joon,Son, Donghee,Kim, Jaemin,Kim, Dong Chan,Choi, Suji,Hong, Jong-In,Kim, Dae-Hyeong American Chemical Society 2017 ACS NANO Vol.11 No.10

<P>With the rapid advances in wearable electronics, the research on carbon-based and/or organic materials and devices has become increasingly important, owing to their advantages in terms of cost, weight, and mechanical deformability. Here, we report an effective material and device design for an integrative wearable cardiac monitor based on carbon nanotube (CNT) electronics and voltage-dependent color-tunable organic light-emitting diodes (CTOLEDs). A p-MOS inverter based on four CNT transistors allows high amplification and thereby successful acquisition of the electrocardiogram (ECG) signals. In the CTOLEDs, an ultrathin exciton block layer of bis[2-(diphenylphosphino)phenyl] ether oxide is used to manipulate the balance of charges between two adjacent emission layers, bis [2-(4,6-difluorophenyl)pyridinato-C-2,N] (picolinato)iridium(III) and bis(2-phenylquinolyl-N,C(2'))iridium(acetylacetonate), which thereby produces different colors with respect to applied voltages. The ultrathin nature of the fabricated devices supports extreme wearability and conformal integration of the sensor on human skin. The wearable CTOLEDs integrated with CNT electronics are used to display human ECG changes in real-time using tunable colors. These materials and device strategies provide opportunities for next generation wearable health indicators.</P>

Small Antimicrobial Peptides from Pharbitis nil

Koo, Ja-Choon,Chun, Hyun-Jin,Cheong Yong-Hwa,Park, Hyeong-Cheol,Han Chang-deok,Lee, Bok-Leul,Cho, Moo-Je Gyeongsang National University, Chinju, Korea 1996 Plant molecular biology and biotechnology research Vol.1996 No.

Stamen-Specific Expression of a Plant Defensin-Type Gene in Chinese Cabbage

Park, Hyeong-Cheol,Cheong, Yong-Hwa,Kim, Min-Chul,Kim, Cha-Young,Koo, Ja-Choon,Chun, Hyun-Jin,Lim, Chae-Oh,Cho, Moo-Je Gyeongsang National University Chinju, Korea 1998 Plant molecular biology and biotechnology research Vol.1998 No.

Stretchable Carbon Nanotube Charge-Trap Floating-Gate Memory and Logic Devices for Wearable Electronics

Son, Donghee,Koo, Ja Hoon,Song, Jun-Kyul,Kim, Jaemin,Lee, Mincheol,Shim, Hyung Joon,Park, Minjoon,Lee, Minbaek,Kim, Ji Hoon,Kim, Dae-Hyeong American Chemical Society 2015 ACS NANO Vol.9 No.5

<P>Electronics for wearable applications require soft, flexible, and stretchable materials and designs to overcome the mechanical mismatch between the human body and devices. A key requirement for such wearable electronics is reliable operation with high performance and robustness during various deformations induced by motions. Here, we present materials and device design strategies for the core elements of wearable electronics, such as transistors, charge-trap floating-gate memory units, and various logic gates, with stretchable form factors. The use of semiconducting carbon nanotube networks designed for integration with charge traps and ultrathin dielectric layers meets the performance requirements as well as reliability, proven by detailed material and electrical characterizations using statistics. Serpentine interconnections and neutral mechanical plane layouts further enhance the deformability required for skin-based systems. Repetitive stretching tests and studies in mechanics corroborate the validity of the current approaches.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/ancac3/2015/ancac3.2015.9.issue-5/acsnano.5b01848/production/images/medium/nn-2015-01848z_0010.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/nn5b01848'>ACS Electronic Supporting Info</A></P>

논문 : 한국 제조업의 지리적 분포, 1909-2003

이윤 ( Yune Lee ),구자형 ( Ja Hyeong Koo ) 경제사학회 2005 經濟史學 Vol.38 No.-

이 논문은 한국에서 사적 소유권과 기업활동의 자유가 법적으로 확립된 이래 이루어진 제조업의 지역별 집적, 특화 그리고 이동성의 추이를 기록하고 분석한다. 분석기간 동안 한국의 경제는 지역별로 분할된 소농 중심의 경제에서 통합된 국민경제로 전화되었으며, 빈곤한 농업국가에서 고도의 산업국가로 성장했다. 그럼에도 불구하고 현재 한국 제조업 고용의 상대적 분포는 1930년대와 크게 다르지 않다. 이것은 식민지기에 건설된 수송망체계가 그 후에도 유지?보강되었기 때문이다. 제조업의 지역특화도는 식민지기 초기에 약간 하강하다가 한국전쟁 이래 상승하여 1985년 정점에 다다른 후 하강한다. 이 추세는 Kim(1995)이 보고한 미국의 경험과 거의 일치한다. 이것은 수송비 하락에 의하여 주로 설명될 수 있다. 특화도의 동태적 분석은 한국 제조업의 이동성이 작지 않았음을 보인다. 따라서 현재 제조업의 지역적 분포가 역사적 우연이나 의도된 정책의 결과가 아니라 시장균형의 산물이라는 것을 알 수 있다. We examine the long-term trends in the regional agglomeration, specialization and mobility of South Korean manufacturing. Korea began to cross-over to a capitalist system in the early 20th century, largely by adopting modern property rights while under the colonial rule of Japan. A rapid growth during this period and market integration resulted in tremendous changes in the Korean economic landscape. By observing these economic changes and other developments, we explore the driving forces that produced the current geographic distribution of manufacturing facilities. We emphasize the role of transportation networks and transport costs in shaping the country‘s regional industrial agglomeration and specialization. The results are consistent with the U.S. experience reported by Kim (1995) and Dumais, Ellison and Glaeser (2002).

Wearable and Implantable Soft Bioelectronics Using Two-Dimensional Materials

Choi, Changsoon,Lee, Youngsik,Cho, Kyoung Won,Koo, Ja Hoon,Kim, Dae-Hyeong American Chemical Society 2019 Accounts of chemical research Vol.52 No.1

<P><B>Conspectus</B></P><P>Soft bioelectronics intended for application to wearable and implantable biomedical devices have attracted great attention from material scientists, device engineers, and clinicians because of their extremely soft mechanical properties that match with a variety of human organs and tissues, including the brain, heart, skin, eye, muscles, and neurons, as well as their wide diversity in device designs and biomedical functions that can be finely tuned for each specific case of applications. These unique features of the soft bioelectronics have allowed minimal mechanical and biological damage to organs and tissues integrated with bioelectronic devices and reduced side effects including inflammation, skin irritation, and immune responses even after long-term biointegration. These favorable properties for biointegration have enabled long-term monitoring of key biomedical indicators with high signal-to-noise ratio, reliable diagnosis of the patient’s health status, and in situ feedback therapy with high treatment efficacy optimized for the requirements of each specific disease model. These advantageous device functions and performances could be maximized by adopting novel high-quality soft nanomaterials, particularly ultrathin two-dimensional (2D) materials, for soft bioelectronics.</P><P>Two-dimensional materials are emerging material candidates for the channels and electrodes in electronic devices (semiconductors and conductors, respectively). They can also be applied to various biosensors and therapeutic actuators in soft bioelectronics. The ultrathin vertically layered nanostructure, whose layer number can be controlled in the synthesis step, and the horizontally continuous planar molecular structure, which can be found over a large area, have conferred unique mechanical, electrical, and optical properties upon the 2D materials. The atomically thin nanostructure allows mechanical softness and flexibility and high optical transparency of the device, while the large-area continuous thin film structure allows efficient carrier transport within the 2D plane. In addition, the quantum confinement effect in the atomically thin 2D layers introduces interesting optoelectronic properties and superb photodetecting capabilities. When fabricated as soft bioelectronic devices, these interesting and useful material features of the 2D materials enable unconventional device functions in biological and optical sensing, as well as superb performance in electrical and biochemical therapeutic actuations.</P><P>In this Account, we first summarize the distinctive characteristics of the 2D materials in terms of the mechanical, optical, chemical, electrical, and biomedical aspects and then present application examples of the 2D materials to soft bioelectronic devices based on each aforementioned unique material properties. Among various kinds of 2D materials, we particularly focus on graphene and MoS<SUB>2</SUB>. The advantageous material features of graphene and MoS<SUB>2</SUB> include ultrathin thickness, facile functionalization, large surface-to-volume ratio, biocompatibility, superior photoabsorption, and high transparency, which allow the development of high-performance multifunctional soft bioelectronics, such as a wearable glucose patch, a highly sensitive humidity sensor, an ultrathin tactile sensor, a soft neural probe, a soft retinal prosthesis, a smart endoscope, and a cell culture platform. A brief comparison of their characteristics and performances is also provided. Finally, this Account concludes with a future outlook on next-generation soft bioelectronics based on 2D materials.</P> [FIG OMISSION]</BR>