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Yoshimasu, Takashi,Hiroi, Akihisa,Ohtani, Toshio,Uede, Koji,Furukawa, Fukumi Korean Society of Photoscience 2002 Journal of Photosciences Vol.9 No.2
Fluorouracil (FU) is well known to induce discoid lupus-like eruption at the sun exposure sites in Japan. It means the associations of UVB with drug induced DLE. It is still obscure which cytokines are involved in the development of DLE. To address the issue, we established a murine model of FU and UVB-induced discoid lupus and could show the Th1 dominant cytokine profiles in DLE model of TCR $\alpha$ chain KO mice treated with FU and UVB.
Low Dose Ultraviolet Al (340-400 nm) Phototherapy for Erythrodermic Cutaneous T-cell Lymphoma
Uede, Koji,Hiroi, Akihisa,Nakamura, Tomoyuki,Kishi, Tomoo,Yamamoto, Yuki,Furukawa, Fukumi Korean Society of Photoscience 2002 Journal of Photosciences Vol.9 No.2
Three patients suffering from widespread erythrodermic cutaneous T-cell lymphoma were treated with low-dose UVAI phototherapy with a single dose of 20 - 30J/$cm^2$, resulting in cumulative doses of 520 - 1890 J/$cm^2$. Two patients showed complete responses, while other had a partial improvement.