한국 청년층（20-39세）의 TyG Index와 hs-CRP 연관성 : 제9기 국민건강영양조사（2024）를 이용하여 = Association between Triglyceride-Glucose Index and High-Sensitivity C-Reactive Protein in Korean Young Adults: Data from the 9th Korea National Health and Nutrition Examination Survey （2024）

다국어 초록 (Multilingual Abstract)

The triglyceride-glucose （TyG） index is a simple surrogate marker of insulin resistance, whereas high-sensitivity C-reactive protein （hs-CRP） is a representative biomarker of systemic inflammation. This cross-sectional study was conducted using data from the 9th Korea National Health and Nutrition Examination Survey （KNHANES, 2024） and included Korean adults aged 20–39 years. Pearson correlation analysis and complex sample multiple linear regression analysis were performed to evaluate the association between the TyG index and hs-CRP. Additional stratified analyses were conducted according to sex, obesity status, and abdominal obesity status.

The TyG index showed a significant positive association with ln（hs-CRP） in the unadjusted model and in models adjusted for selected covariates. However, after further adjustment for body mass index （BMI）, the association was no longer statistically significant, suggesting that BMI may mediate the relationship between the two variables. Stratified analyses by sex and abdominal obesity status revealed no significant associations. In contrast, a significant positive association between the TyG index and ln（hs-CRP） was observed among individuals with obesity.

These findings suggest that obesity may play an important role in the relationship between insulin resistance and systemic inflammation among young Korean adults.

목차 (Table of Contents)

• 제1장 서론 1
• 제1절 연구 배경 1
• 제2장 연구 방법 4
• 제1절 연구 대상 4
• 제2절 조사 변수 5
• 제3절 TyG Index의 측정 5
• 제4절 hs-CRP의 측정 6
• 제5절 통계 분석 6
• 제3장 결과 8
• 제1절 연구대상자의 일반적 특성 8
• 제2절 TyG index와 ln（hs-CRP）의 상관분석 10
• 제3절 TyG index와 ln（hs-CRP）의 연관성: 단계적 복합표본 다중선형회귀분석 11
• 제4절 성별 층화분석 14
• 제5절 비만 여부에 따른 층화분석 16
• 제6절 복부비만 여부에 따른 층화분석 18
• 제4장 고 찰 20
• 1. TyG index와 hs-CRP의 연관성 20
• 2. BMI 보정 후 연관성 소실의 의미 20
• 3. 비만 여부에 따른 층화분석 결과 21
• 4. 성별에 따른 층화분석 결과 22
• 5. 복부비만에 따른 층화분석 결과 22
• 6. 연구의 의의 및 제한점 23
• 제5장 결 론 25
• 참고문헌 27