Purpose: The purpose of this study was to investigate the effects of a physical therapy intervention combined with blood flow restriction (BFR) training on pain, structural changes (pennation angle), muscle strength, function, and psychosocial factors...
Purpose: The purpose of this study was to investigate the effects of a physical therapy intervention combined with blood flow restriction (BFR) training on pain, structural changes (pennation angle), muscle strength, function, and psychosocial factors in patients with chronic lateral epicondylitis (LE).
Methods: This study was a randomized controlled trial. Twenty participants with chronic LE were randomly assigned to an experimental group (EG, n=10) or a control group (CG, n=10). Both groups received general physical therapy and a progressive exercise program (including concentric, eccentric, and isometric exercises) for 60 minutes, twice a week, for 6 weeks. The EG performed the exercise program with BFR applied to the upper arm (at 40~50% of Arterial Occlusion Pressure), while the CG performed the same exercises without BFR. Outcome measures included subjective pain (Numerical Pain Rating Scale [NPRS]), objective pain (pressure pain threshold [PPT]), structural changes (Pennation Angle [PA]), strength (Pain-free grip strength [PFGS], Wrist extensor strength [WES]), function (Patient-Rated Tennis Elbow Evaluation [PRTEE], Quick-Disabilities of the Arm, Shoulder and Hand [Q-DASH]), and psychosocial factors (Fear-Avoidance Beliefs Questionnaire [FABQ], and SF-12 Physical [PCS] and Mental [MCS] Component Summaries). All variables were assessed at baseline and after 6 weeks.
Results: After 6 weeks, both groups showed significant improvements in all dependent variables (all p<.05). In the between-group comparison of change scores, the EG demonstrated significantly greater improvements than the CG in elbow-specific function (PRTEE; p=.000), overall arm function (Quick-DASH; p=.025), fear-avoidance beliefs (FABQ; p=.039), and the physical component summary of quality of life (SF-12 PCS; p=.003). There were no significant between-group differences in pain (NPRS, PPT), pennation angle, strength (PFGS, WES), or the mental component summary of quality of life (SF-12 MCS) (all p>.05).
Conclusion: In conclusion, a 6-week physical therapy program combined with BFR training was significantly more effective in improving patient-rated function (PRTEE, Quick-DASH), reducing fear-avoidance beliefs (FABQ), and enhancing physical health-related quality of life (SF-12 PCS) compared to the same program without BFR. This improvement is likely driven by BFR training acting as a 'safe, low-load' exercise option, which reduces fear of movement and promotes patient-perceived functional recovery, even when objective strength gains are not yet statistically distinct. Therefore, BFR is a promising intervention, especially for patients whose high pain or fear-avoidance limits high-intensity exercise.