In modern society, the production and use of chemicals have rapidly increased, and as a result, indoor environments have garnered attention as significant exposure pathways for chemical pollutants. In particular, indoor dust acts as a repository for p...
In modern society, the production and use of chemicals have rapidly increased, and as a result, indoor environments have garnered attention as significant exposure pathways for chemical pollutants. In particular, indoor dust acts as a repository for pollutants such as flame retardants and plasticizers in enclosed environments. In this study, Target and Suspect screening using liquid chromatography coupled with high-resolution mass spectrometry (LC-HRMS) was performed to characterize contaminants in indoor dust. Eleven dust samples from House (n = 5), Lecture (n = 3), and Offices (n = 3) were analyzed for 59 target compounds and 930 suspects. Target screening detected six compounds (Caffeine, Pentaethylene glycol, Hexaethylene glycol, Dimethyl phthalate (DMP), Diethylene glycol dibenzoate (DEGDB) above the LOQ across all samples. OPFRs (TCEP, TEP, TCPP) were quantified in many samples, with TCPP reaching ≥1,000 ng/g in H1, H3, H4, and O3. Furthermore, L3 sample showed higher levels of TEP (29,437.0 ng/g) and TCEP (24,786.5 ng/g) compared to the other samples. Suspect screening identified PEGs (Deca/ Undeca/ Dodecaethylene glycol) in all samples and nicotine in several samples. DCHA consistently showed large peak areas (10.0E+07–10.0E+8), indicating contributions from rubber or paint materials. 1-Tetradecylamine and DEP were tentatively identified in a subset of samples, whereas piperine was observed in one sample. The results support risk assessment and help prioritize management of indoor chemical exposures.